VIP Nasal Spray

Description

VIP Nasal Spray

This product is intended for research purposes only. To be used by trained professionals only.

Vasoactive Intestinal Peptide (VIP) is a neuroendocrine peptide that has multifaceted physiological roles, making it an essential component in various biological systems [1]. Predominantly produced in the gastrointestinal tract, pancreas, and hypothalamus, VIP exerts its effect through G-protein coupled receptors, specifically VPAC1 and VPAC2 receptors [2].

VIP nasal spray influences a wide range of physiological functions. It acts as a potent vasodilator and bronchodilator, thereby playing a significant role in cardiovascular and respiratory physiology [3]. In the gastrointestinal system, VIP stimulates secretion of water and electrolytes and inhibits gastric acid secretion, thereby contributing to the regulation of gut motility.

Furthermore, VIP nasal spray has been found to have profound effects on the immune system. It exhibits both anti-inflammatory and immunosuppressive activities, which are mediated through inhibition of nuclear factor-kappa B (NF-κB) activation and induction of regulatory T cells, respectively [4]. Because of these properties, VIP is being studied for its potential therapeutic roles in various inflammatory conditions including rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis [5].

In the central nervous system, clinical studies have demonstrated that VIP nasal spray is involved in the regulation of circadian rhythms by influencing the activity of suprachiasmatic nuclei in the hypothalamus [6]. Disruptions in VIP signalling have been linked to sleep disorders, highlighting its importance in maintaining normal sleep-wake cycles.

Recent research also suggests a role for VIP in neuroprotection. Studies have shown that VIP nasal spray can protect neurons against excitotoxicity, oxidative stress, and inflammation, suggesting its potential utility in neurodegenerative disorders such as Alzheimer’s disease [7].

References:

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3046665/

[2] https://pubmed.ncbi.nlm.nih.gov/ 12611609/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC1570498/

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC2288682/

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4939296/

[6] https://www.nature.com/articles/ nrn.2016.77

[7] https://pubmed.ncbi.nlm.nih.gov/ 30498985/

Sequence: HSDAVFTDNYXRLR KQMAVKKYLNSXLN

Molecular Formula: C147H237N43043S

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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