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VIP Nasal Spray

£26.24£47.48

Buy Vasoactive Intestinal Peptide Nasal Spray

Vasoactive Intestinal Peptide (VIP) is a neuropeptide that plays multiple physiological roles, including vasodilation, bronchodilation, gastrointestinal regulation, and immunomodulation. It is produced in many tissues of vertebrates including the gut, pancreas, and suprachiasmatic nuclei of the hypothalamus.

Vasoactive Intestinal Peptide 15ml contains: 2mg
Vasoactive Intestinal Peptide 30ml contains: 4mg

 

Buy 10 and get 10% Discount

448 in stock

Description

VIP Nasal Spray

This product is intended for research purposes only. To be used by trained professionals only.

Vasoactive Intestinal Peptide (VIP) is a neuroendocrine peptide that has multifaceted physiological roles, making it an essential component in various biological systems [1]. Predominantly produced in the gastrointestinal tract, pancreas, and hypothalamus, VIP exerts its effect through G-protein coupled receptors, specifically VPAC1 and VPAC2 receptors [2].

VIP nasal spray influences a wide range of physiological functions. It acts as a potent vasodilator and bronchodilator, thereby playing a significant role in cardiovascular and respiratory physiology [3]. In the gastrointestinal system, VIP stimulates secretion of water and electrolytes and inhibits gastric acid secretion, thereby contributing to the regulation of gut motility.

Furthermore, VIP nasal spray has been found to have profound effects on the immune system. It exhibits both anti-inflammatory and immunosuppressive activities, which are mediated through inhibition of nuclear factor-kappa B (NF-κB) activation and induction of regulatory T cells, respectively [4]. Because of these properties, VIP is being studied for its potential therapeutic roles in various inflammatory conditions including rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis [5].

In the central nervous system, clinical studies have demonstrated that VIP nasal spray is involved in the regulation of circadian rhythms by influencing the activity of suprachiasmatic nuclei in the hypothalamus [6]. Disruptions in VIP signalling have been linked to sleep disorders, highlighting its importance in maintaining normal sleep-wake cycles.

Recent research also suggests a role for VIP in neuroprotection. Studies have shown that VIP nasal spray can protect neurons against excitotoxicity, oxidative stress, and inflammation, suggesting its potential utility in neurodegenerative disorders such as Alzheimer’s disease [7].


References:

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3046665/

[2] https://pubmed.ncbi.nlm.nih.gov/ 12611609/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC1570498/

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC2288682/

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4939296/

[6] https://www.nature.com/articles/ nrn.2016.77

[7] https://pubmed.ncbi.nlm.nih.gov/ 30498985/


Sequence: HSDAVFTDNYXRLR KQMAVKKYLNSXLN

Molecular Formula: C147H237N43043S

Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

Vasoactive Intestinal Peptide (VIP) HPLC 2023 Certificates_DIRECT PEPTIDES

 

 

 

 

 

 

 

 


DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.


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