Humanin Nasal Spray

Description

Buy Humanin Nasal Peptide Spray

This product is intended for research purposes only. To be used by trained professionals only.

Humanin is a mitochondrial-derived peptide (MDP) that has been gaining considerable attention in the scientific community for its potential role in various physiological processes. It was initially discovered due to its neuroprotective effects against Alzheimer’s disease-related insults, wherein it suppresses neuronal cell death triggered by toxic amyloid-beta peptides [1].

Research indicates that Humanin is not just an anti-apoptotic peptide but also plays a significant role in stress resistance [2]. This peptide appears to interfere with Bax activation, a protein involved in programmed cell death, thereby suppressing apoptosis [3]. This property of Humanin could have far-reaching implications in the treatment of apoptosis-related diseases.

Interestingly, studies have shown that Humanin levels are generally higher in multiple species and are linked with increased lifespan and health span. This suggests that Humanin may play a role in modulating aging and health-related factors. An interaction between Humanin and insulin-like growth factor-binding protein 3 (IGFBP-3) has also been identified, which further regulates cell survival and apoptosis [4].

Moreover, recent research has revealed an intriguing aspect of Humanin’s function: it appears to have a regulatory relationship with formyl peptide receptor-like 1 and 2. The N-formylated variant of Humanin is known to suppress cAMP production in certain cells [5]. This discovery broadens our understanding of Humanin’s role in cellular signalling processes.

One study on lung cancer found that the circular RNA circNOL10 inhibits cancer development by promoting SCML1-mediated transcriptional regulation of the Humanin polypeptide family [6]. This finding introduces a new perspective on the potential therapeutic applications of Humanin in cancer treatment. Humanin is a multifaceted peptide with diverse biological functions. Its roles in neuroprotection, stress resistance, apoptosis regulation, and potentially cancer treatment make it a promising focus for future research.

References:

[1] https://www.sciencedirect.com/ science/article/abs/pii/S03043940 02001994

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3705736/

[3] https://www.nature.com/ articles/nature01627

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7343442/

[5] https://www.sciencedirect.com/ science/article/abs/pii/S0006291X 04020418

[6] https://onlinelibrary.wiley.com/ doi/full/10.1002/advs.2018006 54

Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala

Molecular Formula: C121H205F3N34O34S2
Purity: >99.8%

Research use only. Not for human or animal consumption!

DISCLAIMER: We do not supply peptides to any individual under the age of 21. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY in the process of laboratory research by responsible trained and professional individuals. All products listed on this website (https://direct-peptides.com) and provided through Direct Peptides are intended for laboratory research purposes only. The products listed on this website are NOT for human or animal consumption or ingestion of any kind.

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