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Buy Ipamorelin Peptide

Ipamorelin is a synthetic peptide classified as a selective growth hormone secretagogue. It operates by binding to the ghrelin receptor, which stimulates the release of growth hormone (GH) from the pituitary gland, thereby elevating growth hormone levels in the bloodstream.

This increase in GH levels promotes muscle development and growth, enhances metabolism, aids in pain relief, improves cognition and helps reduce body fat. Ipamorelin is noted for its high selectivity, meaning it primarily targets GH release without significantly impacting other hormone levels, such as cortisol, acetylcholine, prolactin, and aldosterone, therefore minimising potential side effects.

Shop our Full Range of Ipamorelin Peptides

What Is The Ipamorelin Mechanism Of Action?

Ipamorelin is a synthetic pentapeptide, meaning it consists of five amino acids, that mimics the growth hormone releasing properties of Ghrelin. It is known as a selective growth hormone secretagogue which operates by mimicking the ghrelin receptor, a hormone that stimulates the release of growth hormone (GH).

When administered, Ipamorelin binds to specific receptors on the pituitary gland, prompting the gland to secrete increased levels of growth hormone into the bloodstream. This increase in growth hormone facilitates muscle growth, fat metabolism, and overall body composition improvement.

Unlike other GH secretagogues, Ipamorelin is noted for its selectivity, meaning it primarily stimulates the release of growth hormone without significantly affecting other hormones like cortisol or prolactin, thereby reducing the likelihood of unwanted side effects. The targeted nature of Ipamorelin makes it a preferred option in peptide therapies aimed at building lean muscle mass and enhancing physical performance.

Structure of Ipamorelin

Ipamorelin Structure
Source: PubChem


Sequence: H-Aib-His-D-2Nal-D-Phe-Lys-NH2

Molecular Formula: C38H49N9O5

Molecular Weight: 711.9 g/mol

What Are The Research Benefits of Ipamorelin Peptide?

Stimulation of Growth Hormone Secretion: Ipamorelin is a potent and selective agonist of the ghrelin and growth hormone secretagogue receptor (GHSR). Research suggests it stimulates the secretion of growth hormone from the pituitary gland, which can lead to increased muscle mass, bone density, and body composition improvements [1].

Side Effects of Ipamorelin are Reduced: Compared to other growth hormone-releasing peptides (GHRPs), research indicates that Ipamorelin has been shown to cause fewer side effects. It does not significantly increase cortisol, prolactin, or acetylcholine levels, thus reducing potential negative impacts on the body’s stress response and cognitive function [1].

Promotion of Slow Wave Sleep (SWS): Research studies indicate that ipamorelin may enhance slow-wave sleep, the deepest stage of non-REM sleep. This is a critical phase for the body’s recovery and regeneration processes [2].

Anti-Aging Properties: Due to its ability to stimulate growth hormone production, research suggests that ipamorelin has potential anti-aging benefits. It may promote skin elasticity, decrease wrinkles, and improve overall vitality [3].

Potential Cardioprotective Effects: Preliminary studies suggest that ipamorelin might have cardioprotective effects. One rodent study found that it reduced heart damage after an ischemic event, potentially via its growth hormone-releasing properties [4].

Increased Lipolysis: According to studies, as a GHRP, Ipamorelin can stimulate lipolysis, the breakdown of fats and lipids. This could potentially lead to weight loss and improved metabolic health [5].

Neuroprotective Capabilities: Some research suggests that ipamorelin may have neuroprotective effects, potentially useful in conditions like Alzheimer’s disease. However, this area needs further exploration [6].

Buy Ipamorelin for research online today!

Buy Ipamorelin and Sermorelin Peptide Stack 2mg Vials


Ipamorelin Sermorelin Peptide Stack
Buy Ipamorelin Sermorelin Peptide Stack


Discover the benefits of combining Ipamorelin and Sermorelin in a peptide stack for optimal growth hormone release. Both are growth hormone-releasing peptides (GHRPs) that work together to boost the body’s natural growth hormone production. Ipamorelin selectively stimulates growth hormone release without significantly affecting other hormones like cortisol and prolactin. Sermorelin mimics the body’s natural growth hormone-releasing hormone (GHRH), targeting the pituitary gland to trigger growth hormone production.

When used together, this peptide stack offers a powerful combination that maximises the benefits of both peptides. Researchers may find that the stack supports studies related to anti-aging, muscle growth, fat loss, and overall vitality. The 2mg formulation provides a precise dosage for controlled research applications.

Our Ipamorelin and Sermorelin Peptide Stack is available in a convenient 2mg vial, ensuring ease of use and accurate measurement for your research needs. By choosing this blend, researchers gain access to a potent tool for exploring the multifaceted roles of growth hormone in health and disease.

Buy Ipamorelin and Sermorelin Peptide Stack 2mg online from Direct Peptides , and experience the superior quality and innovation in peptide research products that we are known for.

Buy Ipamorelin and CJC-1295 no DAC Blend Peptide Nasal Spray

ipamorelin cjc-1295 no dac blend nasal spray 30ml
Buy Ipamorelin and CJC no DAC Blend Nasal Spray

Combining Ipamorelin with CJC without DAC offers a potent blend for researchers exploring growth hormone stimulation. This nasal spray ensures rapid absorption and action, making it an excellent alternative to traditional injections.

Both Ipamorelin and CJC No DAC are growth hormone-releasing peptides (GHRPs) with distinct roles in a blend. Ipamorelin targets growth hormone release without significantly affecting other hormones like cortisol or prolactin, making it a selective peptide with minimal side effects. CJC No DAC stimulates the pituitary gland to release human growth hormone (HGH) in pulses, enhancing Ipamorelin’s function over the long term.

Available in 15ml and 30ml bottles, the nasal spray format is designed for ease of use and better compliance among researchers. This versatile combination is potentially useful for studies on anti-aging, muscle growth, fat loss, and overall vitality. By choosing this blend, researchers gain a powerful tool for exploring growth hormone release and its physiological effects.

Buy Ipamorelin and CJC No DAC Blend Nasal Spray online from Direct Peptides and experience the innovation and quality that define our peptide research products.

Ipamorelin Further Answered Questions (FAQ’s)

What is Ipamorelin used for?

Ipamorelin is primarily used to stimulate the release of growth hormone, which can aid in muscle growth, fat metabolism, and improved body composition. It is commonly used in peptide therapy for enhancing physical performance and for its potential anti-aging benefits.

How does Ipamorelin work?

Ipamorelin works by binding to the ghrelin receptor, which stimulates the pituitary gland to secrete growth hormone into the bloodstream. This increase in growth hormone leads to various physiological benefits such as increased muscle mass and improved metabolism.

Are there any side effects associated with Ipamorelin?

Ipamorelin is noted for its selectivity and is associated with fewer side effects compared to other growth hormone-releasing peptides. It does not significantly affect cortisol, prolactin, or acetylcholine levels, thus reducing the risk of unwanted side effects.

Is Ipamorelin legal?

The legality of Ipamorelin varies by country and its intended use. In the United States, for example, Ipamorelin is classified as a research chemical and is not approved by the FDA (Food and Drug Administration) for human use. Therefore, you can only buy Ipamorelin for research purposes, but its use in sports or for personal health benefits may fall under regulations set by various sporting and governmental bodies.

In the United Kingdom, the regulatory body responsible for such substances is the Medicines and Healthcare products Regulatory Agency (MHRA). The MHRA has not authorised Ipamorelin for human use, and it may only be used under specific research conditions.

Similarly, in Australia, the Therapeutic Goods Administration (TGA) oversees the regulation of medicines, and you can only buy Ipamorelin for research purposes. Always check local laws and consult with a healthcare professional before using Ipamorelin.

Can Ipamorelin help with fat loss?

Yes, Ipamorelin can help with fat loss by enhancing lipolysis, the process by which fats and lipids are broken down. This can lead to a reduction in body fat and an improvement in overall metabolic health.

How is Ipamorelin administered?

Ipamorelin is typically administered through subcutaneous or intramuscular injections. The dosage and frequency of administration should be determined by a healthcare professional based on individual needs and goals.

How long does it take to see results from Ipamorelin?

Results from Ipamorelin can vary based on factors such as dosage, frequency of administration, and individual response. Some users may begin to notice improvements in muscle mass, fat loss, and overall vitality within a few weeks.

Is Ipamorelin safe for long-term use?

While Ipamorelin is generally considered safe and well-tolerated, long-term use should be monitored by a healthcare professional to ensure that it continues to be effective and to minimise any potential risks.

Does Ipamorelin have anti-aging benefits?

Yes, research suggests that Ipamorelin can have anti-aging benefits due to its ability to increase growth hormone levels. This can promote skin elasticity, reduce wrinkles, and improve overall vitality.

Can Ipamorelin enhance sleep quality?

Some studies indicate that Ipamorelin may enhance slow-wave sleep, which is the deepest stage of non-REM sleep essential for the body’s recovery and regeneration processes.

How does Ipamorelin compare to other growth hormone-releasing peptides?

Ipamorelin is often preferred due to its high selectivity and reduced side effects. Unlike other peptides, it primarily stimulates growth hormone release without significantly affecting other hormones like cortisol and prolactin.

Summary of Research Applications

  • Stimulates growth hormone release without impacting cortisol or prolactin levels.
  • May help reduce age-related declines in muscle mass, skin elasticity, and vitality.
  • Potential treatment of muscle-wasting conditions and obesity due to growth hormone increasing muscle growth and fat loss.
  • Its effect on growth hormone secretion may enhance bone density, making it significant for osteoporosis and bone disorder research.
  • May aid injury recovery and rehabilitation by stimulating growth hormone release, potentially leading to faster healing and improved tissue repair.
  • Ongoing research explores the impact of Ipamorelin on metabolic health, including insulin sensitivity and fat metabolism. This could have implications for diabetes and other metabolic conditions.


Buy Ipamorelin Peptide from Direct Peptides online, a trusted supplier of quality research peptides.

Ipamorelin Peptide Quality Assured

At Direct Peptides, we take pride in delivering high-quality, pure Ipamorelin peptides. Our strict manufacturing and quality control ensure each batch meets industry standards. With at least 99% purity, our Ipamorelin peptide is a benchmark of excellence in the research community.

Our commitment to quality starts with selecting premium raw materials and extends through a meticulous synthesis and purification process. Each batch undergoes comprehensive testing, including mass spectrometry and high-performance liquid chromatography (HPLC), to verify its purity and potency. This rigorous approach ensures researchers receive a consistent, reliable product for precise and impactful studies.

By choosing Direct Peptides, you can trust in the quality of our Ipamorelin peptides for advanced research into growth hormone stimulation, anti-aging, muscle growth, and more. Our dedication to excellence supports your scientific endeavors, providing a solid foundation for groundbreaking discoveries and innovative applications.

View the HPLC Certificate here.

References For Further Reading​

[1] K Raun, B S Hansen, N L Johansen, et al (1998) Ipamorelin, the first selective growth hormone secretagogue – European Journal of Endocrinology, 1998 Nov, Volume 139 (Issue 5), Pages 552-61.

[2] E Szentirmai, I Hajdu, F Obal Jr, and J M Krueger (2006) Ghrelin-induced sleep responses in ad libitum fed and food-restricted rats – Brain Research Bulletin, 2006 May 30, Volume 69 (Issue 5), Pages 452-60.

[3] M Bex, R Abs, D Maiter, et al (2002) The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: a 2-year open randomized controlled multicenter trial – Journal of Bone Mineral Research, 2002 Jun, Volume 17 (Issue 6), Pages 1081-94.

[4] F Camanni, E Ghigo, and E Arvat (1998) Growth hormone-releasing peptides and their analogs – Frontiers in Neuroendocrinology, 1998 Jan, Volume 19 (Issue 1), Pages 47-72.

[5] T.D. Müller, R. Nogueiras, M.L. Andermann, et al (2015) Ghrelin – Molecular Metabolism, 2015 Jun, Volume 4 (Issue 6), Pages 437–460.

[6] M Moon, H G Kim, L Hwang, et al (2009) Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease by blocking microglial activation – Neurotoxicity Research, 2009 May, Volume 15 (Issue 4), Pages 332-47.

Why Choose Direct Peptides ?

Buy Ipamorelin peptides today and experience the unparalleled quality that Direct Peptides offers. As your leading source for Ipamorelin peptides, we provide a diverse range of Ipamorelin formulations to suit various research needs. Our collection includes peptide vials available in 2mg and 5mg sizes, peptide blends and stacks with potential synergistic effects, peptide nasal sprays offered in 15ml and 30ml spray bottles, and pre-mixed peptide pens. At Direct Peptides, we ensure that researchers have access to the precise formulation necessary for their unique research projects, upholding the highest standards of purity and effectiveness in our products.


DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.