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Highest Quality | For Research Use Only

Hexarelin

Buy Hexarelin Peptide

Hexarelin peptide, a synthetic hexapeptide, is primarily recognized for its capacity to stimulate the release of growth hormone (GH). It’s structurally similar to growth hormone-releasing peptides (GHRPs), which include GHRP-2 and GHRP-6.

Hexarelin functions by binding to the ghrelin/growth hormone secretagogue receptor (GHSR) located in the pituitary and hypothalamic region. This binding triggers an increase in intracellular calcium levels, leading to the stimulation of growth hormone release. Studies have shown that Hexarelin exhibits a more potent GH-releasing effect compared to other GHRPs, positioning it as a promising candidate for further exploration in the realm of endocrinology.

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Potential Benefits of Hexarelin Peptide

  • Cardiovascular Effects: Acute administration of Hexarelin has been observed to exert a short-lasting, positive inotropic effect, which is independent of growth hormone (GH) activity [1]. This suggests potential benefits for cardiovascular health.
  • Bone Health: Hexarelin, a growth hormone–releasing peptide, has been shown to counteract bone loss in gonadectomized male rats [2]. This could imply a potential therapeutic role in conditions that cause bone loss.
  • Cardioprotective Role: The peptide has been found to protect against myocardial infarction and can prevent the death of cardiomyocytes [3] and [4]. It’s also been found to attenuate abdominal aortic aneurysm formation [3].
  • Endocrine and Metabolic Effects: Hexarelin has demonstrated significant endocrine and metabolic effects in obese Zucker rats [5]. This may suggest potential applications in metabolic disorder management.
  • Potential Therapeutic Benefits: Hexarelin is a stable and effective Growth Hormone Secretagogue (GHS) that can potentially be used therapeutically [6]. Additionally, it has been researched for its possible utility in improving athletic performance and treating diseases that cause muscle wasting [7].
  • Role in Diabetes and Associated Heart Diseases: Ghrelin and hexarelin, have been shown to exert GH-independent cardiovascular activity. They play physiological roles in the protection against diabetes and associated heart diseases [8].

References

[1] https://pubmed.ncbi.nlm.nih.gov/10342360/

[2] https://pubmed.ncbi.nlm.nih.gov/10512687/

[3] https://pubmed.ncbi.nlm.nih.gov/34856183/

[4] https://pubmed.ncbi.nlm.nih.gov/14615277/

[5] https://pubmed.ncbi.nlm.nih.gov/10974647/

[6] https://pubmed.ncbi.nlm.nih.gov/8762732/

[7] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5638899/

[8] https://pubmed.ncbi.nlm.nih.gov/25645463/

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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