Nontoxic protein that can selectively bind to receptors present in cancer cells to cause cell death. PNC-27 is a membrane-active peptide that binds to the HDM-2 protein found in cancer cells membranes. Of healthy tissue tumour cells and generates transmembrane pore development in cancer. However, not in typical cells, resulting in tumour cell necrosis that is independent of p53 activity in these cells.

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555 in stock


Buy PNC-27 Peptide Vial 5mg 

This product is intended for research and medical purposes only, to be only used by trained professionals.

PNC-27 is a synthetic peptide. Pnc 27 peptide research suggests cancerous cells and triggers necrosis, resulting in cell death. In addition, an HDM-2 binding domain in the peptide allows it to membranolyze cancer cells and kill them.

The peptide pnc 27 scientific studies suggest it appears to be highly effective in treating a variety of cancers, including breast cancer, melanoma, pancreatic cancer, and leukaemia, according to studies [i]on animal subjects.

Some studies have suggested in contrast to chemotherapy, which targets healthy cells, PNC-27 cancer peptide targets cancer cells. When it attaches to cancer cells, it makes holes in their membranes, causing them to die quickly.

Scientists had intended to use PNC to fight HIV until it was discovered that it could also be used to destroy cancer cells while not harming healthy ones. Few clinical trials using Pnc 27 since then have shown that it is effective in combating cancer.

PNC 27’s mechanism of action, according to the study’s, is caused by the formation of oligomeric pores in cancer cells’ plasma membranes. Researchers, therefore, concluded that these findings confirm cancer cells’ unique localization of MDM2 variants. Consequently, it was also stated that the future anticancer treatment of pnc-27peptide shows excellent promise.



Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

Disclaimer: We do not supply peptides to Any individual under the age of 18. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY FOR medical research by responsible trained and professional individuals. All products listed on this website ( and provided through Direct Peptides are intended for medical research purposes only. Direct Peptides does not encourage or promote the use of any of these products in a personal capacity (i.e. human consumption), nor are the products intended as a drug, stimulant or for use in any food products.