PNC-27 Nasal Spray


PNC-27 is a synthesized anti-cancer peptide that inhibits HDM-2’s interaction with the tumour suppressor protein p53 by binding to it. According to scientific studies, it selectively destroys cancer cells by inducing membranolysis (collapse of the cell membrane).

PNC-27 15ml contains: 5mg
PNC-27 30ml contains: 10mg

Buy 10 and get 10% Discount
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499 in stock



This product is intended for research and medical purposes only, to be only used by trained professionals.

PNC-27 is a synthetic peptide. PNC-27 peptide research suggests it triggers necrosis in cancerous cells, resulting in cell death. In addition, an HDM-2 binding domain in the peptide allows it to membranolyze cancer cells and kill them.

The peptide PNC-27 scientific studies suggest it appears to be highly effective in treating various cancers, including breast cancer, melanoma, pancreatic cancer, and leukaemia, according to studies on animal subjects.

Some studies have suggested that, in contrast to chemotherapy, which targets healthy cells, PNC-27 cancer peptide targets cancer cells. When it attaches to cancer cells, it makes holes in their membranes, causing them to die quickly.

Scientists had intended to use PNC to fight HIV until it was discovered that it could also be used to destroy cancer cells while not harming healthy ones. Unfortunately, few clinical trials using PNC 27 since then have shown that it is effective in combating cancer.

According to the studies, PNC-27’s mechanism of action is caused by the formation of oligomeric pores in cancer cells’ plasma membranes. Researchers, therefore, concluded that these findings confirm cancer cells’ unique localization of MDM2 variants. Consequently, it was also stated that the future anticancer treatment of PNC-27 peptide shows excellent promise.



Storage: Lyophilized peptides stored below -18°C.

Research use only. Not for human or animal consumption!

Disclaimer: We do not supply peptides to Any individual under the age of 18. You must be a licensed and qualified healthcare practitioner. Our team of dedicated professionals are committed to providing an extensive range of products used ONLY FOR medical research by responsible trained and professional individuals. All products listed on this website ( and provided through Direct Peptides are intended for medical research purposes only. Direct Peptides does not encourage or promote the use of any of these products in a personal capacity (i.e. human consumption), nor are the products intended as a drug, stimulant or for use in any food products.

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