Mots-C

Description

Mots-c Peptide Vial 10mg

This product is intended for research purposes only. To be used by trained professionals only.

Research has suggested MOTS-c is an exercise mimetic, a 16-amino-acid peptide that is encoded in the mitochondrial genome of cells. According to clinical studies, it improves insulin sensitivity. While the study is still ongoing, control group examinations using diet-induced obese mice have shown improvements in insulin sensitivity. Researchers are still studying to see if the MOTS-c changes plasma markers, which are used to determine the body’s metabolic condition [1].

Research has shown that it targets body muscles and regulates its metabolism using the folate-purine-AMPK pathway. By doing so, it becomes effective protecting against obesity and insulin resistance that stems from the diet that one is taking or age.

Clinical studies have shown that MOTS-c promotes the production of endogen AMP analogue AICAR, which in turn, helps in the synthesis of AMP-activated protein kinase [2] (also referred to as AMPK). Before the production of AMPK, its cellular actions inhibit the folate cycle along with de novo purine biosynthesis. The AMPK then induces systemic cellular uptake of glucose and enhances insulin sensitivity. These studies suggest the mitochondria [3] offer active regulation of metabolic homeostasis via this peptide encoded in their genome.

Research has confirmed that the peptide genome can help reduce insulin resistance [4]. Health experts recommend taking the medication along with a strict, balanced diet to lower the amount of fat taken to manage obesity. Other studies have shown that general weight gain may increase insulin insensitivity, especially on diabetes type 1 patients. Cutting down the fat intake and increased levels of MOTS-c may lower the diet-induced metabolic dysfunction and associated inflammation [5].

References:

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7817689/

[2] https://physoc.onlinelibrary. wiley.com/ doi/full/10.14814/phy2. 14171

[3] https://www.cell.com/article/ s1550-4131(15)00061-3/abs

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5801219/

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4350682/

Sequence:Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular Formula: C101H152N28O22S2

Molecular Weight: 2174.64 f/mol

Storage: Lyophilized peptides to be stored below -18°C

Research use only. Not for human or animal consumption!

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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