KPV Nasal Peptide Spray
This product is intended for research purposes only. To be used by trained professionals only.
The KPV nasal spray peptide is a naturally occurring tripeptide composed of lysine, proline, and valine, is gaining significant attention in the scientific community for its range of potential therapeutic applications. Notably, its anti-inflammatory properties have been highlighted across several studies, with implications for a variety of health conditions.
Research showed that KPV peptides elevated intracellular calcium in human keratinocyte cells, a critical process for skin cell function and regeneration . This suggests that KPV could be beneficial in the treatment of skin disorders such as acne, eczema, and psoriasis. Furthermore, another study in the reported that KPV inhibited the migration of polymorphonuclear leukocytes (PMNs) and the generation of proinflammatory mediators in a model of urate peritonitis .
In the field of gastroenterology, KPV nasal spray has shown potential in the treatment of inflammatory bowel diseases. A study discovered that the PepT1-mediated tripeptide KPV reduced intestinal inflammation , suggesting a possible role in managing conditions like ulcerative colitis and irritable bowel syndrome. Moreover, KPV peptide has been explored as a target for fluorescent probes in imaging studies of chronic and acute ulcerative colitis .
KPV’s role in tumorigenesis attenuation has also been investigated. One study suggested that KPV nasal spray may decrease the progression of colitis-associated cancer . Additionally, research on antimicrobial peptides indicated potential therapeutic applications of a dimeric octamer peptide comprising two units of KPV peptide connected by a cysteine-cysteine linker .
 https://www.sciencedirect.com/ science/article/pii/S0022202X 15307697
 https://jpet.aspetjournals.org/ content/306/2/631.short
 https://www.sciencedirect.com/ science/article/abs/pii/S00165085 07018525
 https://pubs.acs.org/doi/abs/ 10.1021/acsami.7b00936
 https://www.sciencedirect.com/ science/article/pii/S2352345X1 6000151
 https://www.mdpi.com/ 1420-3049/17/10/12276
Molecular Formula: C16H30N404
Molecular Weight: 342.43 g/mol
Storage: Lyophilized peptides stored below -18°C.
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