KPV Nasal Spray

Description

KPV Nasal Peptide Spray

This product is intended for research purposes only. To be used by trained professionals only.

The KPV nasal spray peptide is a naturally occurring tripeptide composed of lysine, proline, and valine, is gaining significant attention in the scientific community for its range of potential therapeutic applications. Notably, its anti-inflammatory properties have been highlighted across several studies, with implications for a variety of health conditions.

Research showed that KPV peptides elevated intracellular calcium in human keratinocyte cells, a critical process for skin cell function and regeneration [1]. This suggests that KPV could be beneficial in the treatment of skin disorders such as acne, eczema, and psoriasis. Furthermore, another study in the reported that KPV inhibited the migration of polymorphonuclear leukocytes (PMNs) and the generation of proinflammatory mediators in a model of urate peritonitis [2].

In the field of gastroenterology, KPV nasal spray has shown potential in the treatment of inflammatory bowel diseases. A study discovered that the PepT1-mediated tripeptide KPV reduced intestinal inflammation [3], suggesting a possible role in managing conditions like ulcerative colitis and irritable bowel syndrome. Moreover, KPV peptide has been explored as a target for fluorescent probes in imaging studies of chronic and acute ulcerative colitis [4].

KPV’s role in tumorigenesis attenuation has also been investigated. One study suggested that KPV nasal spray may decrease the progression of colitis-associated cancer [5]. Additionally, research on antimicrobial peptides indicated potential therapeutic applications of a dimeric octamer peptide comprising two units of KPV peptide connected by a cysteine-cysteine linker [6].

References:

[1] https://www.sciencedirect.com/ science/article/pii/S0022202X 15307697

[2] https://jpet.aspetjournals.org/ content/306/2/631.short

[3] https://www.sciencedirect.com/ science/article/abs/pii/S00165085 07018525

[4] https://pubs.acs.org/doi/abs/ 10.1021/acsami.7b00936

[5] https://www.sciencedirect.com/ science/article/pii/S2352345X1 6000151

[6] https://www.mdpi.com/ 1420-3049/17/10/12276

Sequence: Lys-Pro-Val

Molecular Formula: C16H30N404

Molecular Weight: 342.43 g/mol

Storage: Lyophilized peptides stored below -18°C.

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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